{"id":37335,"date":"2025-03-08T20:40:18","date_gmt":"2025-03-08T20:40:18","guid":{"rendered":"https:\/\/aso-labor.de\/branchen\/medical-devices\/"},"modified":"2026-01-28T01:39:03","modified_gmt":"2026-01-28T01:39:03","slug":"medical-devices","status":"publish","type":"branchen","link":"https:\/\/aso-labor.de\/en\/industries\/medical-devices\/","title":{"rendered":"Medical Devices"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"37335\" class=\"elementor elementor-37335 elementor-33811\" data-elementor-post-type=\"branchen\">\n\t\t\t\t<div class=\"elementor-element elementor-element-37c0843 e-flex e-con-boxed cmsmasters-block-default e-con e-parent\" data-id=\"37c0843\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-602b9a8 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"602b9a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Medical Devices<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b36239c cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-image\" data-id=\"b36239c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"612\" height=\"408\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Medizinprodukte.webp\" class=\"attachment-full size-full wp-image-37356\" alt=\"Medizinprodukte Pr\u00fcfung ASO Labor\" srcset=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Medizinprodukte.webp 612w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Medizinprodukte-300x200.webp 300w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Medizinprodukte-450x300.webp 450w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Medizinprodukte-30x20.webp 30w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Medizinprodukte-15x10.webp 15w\" sizes=\"auto, (max-width: 612px) 100vw, 612px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a42f928 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"a42f928\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Analytics in a Regulated Environment<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5496030 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"5496030\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Manufacturers of medical devices face specific challenges, such as national medical approvals. New or modified products, as well as the development of new markets, often require special tests. Analytik Service Obernburg supports you in advance with expert consulting.  <\/p><p>Our service portfolio includes the control of active ingredient content and the testing for impurities. Furthermore, we offer comprehensive raw material and product analyses, as well as failure analysis for medical technology products. We employ a broad spectrum of analytical and physical methods to ensure the highest quality standards.  <\/p><ul><li>Material Identification and Quantification using NMR (400 MHz)<\/li><li>Active and Excipient Content using HPLC<\/li><li>Spectroscopy, for example on functionalized surfaces<\/li><li>XRD for Determining Phase Purity (Crystalline Structure)<\/li><li>Trace Element Impurities (ICP-MS)<\/li><\/ul><p>Our services are applicable to a variety of issues, including the analysis of the structure, composition, and arrangement of membranes for filtration or dialysis. We also examine medical textiles, reaction vessels, cannulas, contact lenses, and bone substitutes <span style=\"font-weight: 400;\">or their raw materials.<\/span> <\/p><p>We are your high-performance analytics partner for medical devices!<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5745724 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"5745724\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>We are happy to support you in monitoring your raw materials, intermediate, and\/or finished products according to the methods of the European Pharmacopoeia (Ph. Eur. 10).<\/p><p>We would be pleased to provide you with a customized offer!<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a60291 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"1a60291\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><strong>Our analytical spectrum includes the following standards, which we offer accredited in the field of bone cement and bone substitute materials:<\/strong><\/p><p><span style=\"font-weight: 400;\">ISO 13779-3 Characterization of Hydroxyapatite regarding Crystallinity, Phase Purity, and Ca\/P Ratio<\/span><\/p><p><span style=\"font-weight: 400;\">ISO 13779-3 (2018-12): Surgical implants &#8211; Hydroxyapatite &#8211; Part 3: Chemical analysis and characterization of crystallinity ratio and phase purity<\/span><\/p><p><span style=\"font-weight: 400;\">ISO 13320 (2020-01): Particle Size Analysis &#8211; Particle Measurement by Laser Diffraction<\/span><\/p><p><span style=\"font-weight: 400;\"> ISO 14703 (2008-04): Advanced Technical Ceramics &#8211; Sample Preparation for the Determination of Particle Size Distribution of Ceramic Powders <\/span><\/p><p><span style=\"font-weight: 400;\">ISO 24235 (2007-04): Advanced Technical Ceramics &#8211; Determination of Particle Size Distribution of Ceramic Powders by Laser Diffraction<\/span><\/p><p><span style=\"font-weight: 400;\">ISO 5833-1 Stability of Acrylic-based Bone Cement Raw Materials<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-056839d cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"056839d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Our Analytical Spectrum<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5422570 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-text-editor\" data-id=\"5422570\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div id=\"comp-lxivkk7q\" data-testid=\"richTextElement\"><h3>Physical Properties<\/h3><ul><li>Density<\/li><li>Refractive Index<\/li><li>Melting Point \u2013 Capillary Method<\/li><li>Density of Solids<\/li><\/ul><h3>Spectroscopy<\/h3><ul><li>IR \/ Raman Spectroscopy<\/li><li>UV-Vis Spectroscopy<\/li><li>NMR Spectroscopy (in solution, 400 MHz)<\/li><li>X-ray Fluorescence Analysis (XRF)<\/li><\/ul><h3>Chromatography and Viscosity<\/h3><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gas (GC\/MS) and High-Performance Liquid Chromatography (HPLC)<\/span><\/li><li>GPC \/ SEC<\/li><li>Capillary Viscometry<\/li><\/ul><h3>Other Methods<\/h3><ul><li>Thermal Analysis: TGA and DSC<\/li><li>Optical Microscopy<\/li><li>Scanning Electron Microscopy (SEM-EDX)<\/li><li>Particle Size Analysis by Laser Diffraction <\/li><li>Total Carbon Content in Water<\/li><\/ul><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8a9ff20 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-spacer\" data-id=\"8a9ff20\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4097e77 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"4097e77\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Our Experts<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc5240b e-flex e-con-boxed cmsmasters-block-default e-con e-parent\" data-id=\"cc5240b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-58bc535 e-grid e-con-full cmsmasters-block-default e-con e-child\" data-id=\"58bc535\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-630ed40 e-con-full e-flex cmsmasters-block-default e-con e-child\" data-id=\"630ed40\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-224f0eb cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-image\" data-id=\"224f0eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"432\" height=\"418\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Andre-Muthig-1.jpg.avif\" class=\"attachment-full size-full wp-image-37191\" alt=\"ASO Andre Muthig 1.jpg\" srcset=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Andre-Muthig-1.jpg.avif 432w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Andre-Muthig-1.jpg-300x290.avif 300w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Andre-Muthig-1.jpg-310x300.avif 310w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Andre-Muthig-1.jpg-30x30.avif 30w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Andre-Muthig-1.jpg-10x10.avif 10w\" sizes=\"auto, (max-width: 432px) 100vw, 432px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c921571 e-flex e-con-boxed cmsmasters-block-default e-con e-child\" data-id=\"c921571\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c52ea85 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"c52ea85\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Dr. Andr\u00e9 Muthig<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d1649bb cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"d1649bb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">NMR Spectroscopy Chromatography <p><\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ec6bb1f cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-spacer\" data-id=\"ec6bb1f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f811958 elementor-icon-list--layout-traditional elementor-list-item-link-full_width cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-icon-list\" data-id=\"f811958\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:andre.muthig@aso-labor.de\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">andre.muthig@aso-labor.de<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"tel:+496022812451\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-phone-alt\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M497.39 361.8l-112-48a24 24 0 0 0-28 6.9l-49.6 60.6A370.66 370.66 0 0 1 130.6 204.11l60.6-49.6a23.94 23.94 0 0 0 6.9-28l-48-112A24.16 24.16 0 0 0 122.6.61l-104 24A24 24 0 0 0 0 48c0 256.5 207.9 464 464 464a24 24 0 0 0 23.4-18.6l24-104a24.29 24.29 0 0 0-14.01-27.6z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">+49 6022 81-2451<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f2df62d e-con-full e-flex cmsmasters-block-default e-con e-child\" data-id=\"f2df62d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-06e4b80 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-image\" data-id=\"06e4b80\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"432\" height=\"418\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Rainer-Ziel.jpg.avif\" class=\"attachment-large size-large wp-image-37188\" alt=\"ASO Rainer Ziel.jpg\" srcset=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Rainer-Ziel.jpg.avif 432w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Rainer-Ziel.jpg-300x290.avif 300w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Rainer-Ziel.jpg-310x300.avif 310w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Rainer-Ziel.jpg-30x30.avif 30w, https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ASO_Rainer-Ziel.jpg-10x10.avif 10w\" sizes=\"auto, (max-width: 432px) 100vw, 432px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b00e808 e-flex e-con-boxed cmsmasters-block-default e-con e-child\" data-id=\"b00e808\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b0eaac0 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"b0eaac0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Rainer Ziel<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a1b205 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"2a1b205\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Failure Analysis, Microscopy\nSurface Analysis<\/p>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d4b82c9 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-spacer\" data-id=\"d4b82c9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c28d3c7 elementor-icon-list--layout-traditional elementor-list-item-link-full_width cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-icon-list\" data-id=\"c28d3c7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:rainer.ziel@aso-labor.de\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">rainer.ziel@aso-labor.de<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"tel:+496022812645\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-phone-alt\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M497.39 361.8l-112-48a24 24 0 0 0-28 6.9l-49.6 60.6A370.66 370.66 0 0 1 130.6 204.11l60.6-49.6a23.94 23.94 0 0 0 6.9-28l-48-112A24.16 24.16 0 0 0 122.6.61l-104 24A24 24 0 0 0 0 48c0 256.5 207.9 464 464 464a24 24 0 0 0 23.4-18.6l24-104a24.29 24.29 0 0 0-14.01-27.6z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">+49 6022 81-2645<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-414b016 e-flex e-con-boxed cmsmasters-block-default e-con e-parent\" data-id=\"414b016\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cb26462 cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-spacer\" data-id=\"cb26462\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d28fc4d cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-heading\" data-id=\"d28fc4d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Application Examples<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div data-separate-animation-selector=\".elementor-widget-cmsmasters-toggles__item\" data-text-animation-class=\"sequental, random\" class=\"elementor-element elementor-element-450e55b cmsmasters-title-alignment-left cmsmasters-item-icon-position-left cmsmasters-trigger-icon-view-default cmsmasters-block-default cmsmasters-sticky-default elementor-widget elementor-widget-cmsmasters-toggles cmsmasters-widget-toggles\" data-id=\"450e55b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;toggles&quot;:[{&quot;toggle_title&quot;:&quot;Material Identification with NMR&quot;,&quot;toggle_content&quot;:&quot;&lt;h4&gt;Material Identification in Medical Technology&lt;\\\/h4&gt;\\n&lt;h5&gt;Problem Statement&lt;\\\/h5&gt;\\n&lt;p&gt;The characterization of medical devices or their underlying raw materials often requires the use of a broad spectrum of analytical and physical methods. This involves a significant time commitment.&lt;br \\\/&gt;However, in many cases, quick material information is needed first, which is then refined later with further analyses. &lt;\\\/p&gt;\\n&lt;h5&gt;Solution&lt;\\\/h5&gt;\\n&lt;p&gt;A versatile method for quickly gaining an overview of a medical device is high-resolution NMR spectroscopy.&lt;br \\\/&gt;It is a method for detailed structural elucidation and quantification of organic substances.&lt;br \\\/&gt;NMR spectroscopy is applicable to all types of organic compounds, including polymers.&lt;br \\\/&gt;Mixtures can be quantified and impurities detected.&lt;\\\/p&gt;\\n&lt;h5&gt;Industries &amp; Applications&lt;\\\/h5&gt;\\n&lt;p&gt;&lt;strong&gt;Medical Technology&lt;\\\/strong&gt; \\u2013 Identification of materials and impurities in complex product structures.&lt;\\\/p&gt;\\n&lt;h5&gt;Analysis Objectives&lt;\\\/h5&gt;\\n&lt;p&gt;Rapid material overview for complex matrices for targeted selection of further test procedures.&lt;\\\/p&gt;\\n&lt;h5&gt;Materials&lt;\\\/h5&gt;\\n&lt;p&gt;Composite Materials, Product Formulations&lt;\\\/p&gt;\\n&lt;h5&gt;Analysis Methods&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;\\u00b9H-NMR (Nuclear Magnetic Resonance)&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Complementary Methods&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Extraction&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Related Issues&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Purity Determinations&lt;\\\/li&gt;\\n&lt;li&gt;Release Analytics&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h4&gt;Example \\u2013 Heat Patch&lt;\\\/h4&gt;\\n&lt;p&gt;In a commercially available heat patch, the active ingredient &lt;strong&gt;Nonivamide&lt;\\\/strong&gt; is detectable in the spectrum after simple extraction with dichloromethane.&lt;br \\\/&gt;However, further information on the carrier liquid &lt;strong&gt;(1,2-propanediol)&lt;\\\/strong&gt;,&lt;br \\\/&gt;preservative &lt;strong&gt;(4-hydroxybenzoate)&lt;\\\/strong&gt;, adhesive &lt;strong&gt;(acrylate)&lt;\\\/strong&gt;, and fabric material &lt;strong&gt;(polyester)&lt;\\\/strong&gt; can also be read from the spectrum.&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35774\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/beispiel-WAeRMEPFLASTER.jpeg\\&quot; alt=\\&quot;\\&quot; width=\\&quot;448\\&quot; height=\\&quot;301\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;h4&gt;Example \\u2013 Warming Ointment&lt;\\\/h4&gt;\\n&lt;p&gt;In comparison, a spectrum excerpt (only the aromatic region) of the CDCl\\u2083 extract of a warming ointment is shown.&lt;br \\\/&gt;Even without prior processing of the ointment material, the active ingredients &lt;strong&gt;Nicoboxil&lt;\\\/strong&gt; and &lt;strong&gt;Nonivamide&lt;\\\/strong&gt;&lt;br \\\/&gt;can be identified and approximately quantified despite the presence of the ointment base.&lt;\\\/p&gt;\\n&lt;p&gt;The quantitative ratio of Nicoboxil to Nonivamide is determined from this spectrum to be approximately &lt;strong&gt;91:9&lt;\\\/strong&gt;,&lt;br \\\/&gt;the package insert for the warming ointment states &lt;strong&gt;86:14&lt;\\\/strong&gt;.&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35775\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/beispiel-waermesalbe.jpeg\\&quot; alt=\\&quot;\\&quot; width=\\&quot;461\\&quot; height=\\&quot;361\\&quot;&gt;&lt;\\\/p&gt;\\n&quot;,&quot;_id&quot;:&quot;8b62f61&quot;,&quot;item_icon&quot;:{&quot;value&quot;:&quot;far fa-file-pdf&quot;,&quot;library&quot;:&quot;fa-regular&quot;},&quot;content_type&quot;:&quot;toggle-content&quot;,&quot;saved_section&quot;:null,&quot;saved_template&quot;:null,&quot;toggle_custom_id&quot;:&quot;&quot;},{&quot;toggle_title&quot;:&quot;Analytics in Medical Technology&quot;,&quot;toggle_content&quot;:&quot;&lt;h4&gt;Medical Technology&lt;\\\/h4&gt;\\n&lt;p&gt;Medical technology involves the interaction of materials science disciplines with medicine and pharmacy.&lt;br \\\/&gt;Only through this connection is the development and application of complex medical devices possible.&lt;\\\/p&gt;\\n&lt;p&gt;An example of this is artificial blood purification using hemodialysis. Here \\u2013 as shown in Fig. 1 \\u2013 a patient&#039;s blood is passed through a dialyzer outside their body and then returned.&lt;br \\\/&gt;In the dialyzer, toxins are filtered out of the blood through small pores, while vital components remain in the blood.&lt;br \\\/&gt;Further components of a dialysis machine include the blood pump, tubing systems, and measurement and monitoring devices. Additionally, a medication that acts as an anticoagulant can be administered via the dialysis machine.   &lt;\\\/p&gt;\\n&lt;p&gt;The various components used here must meet high material-technical and medical requirements.&lt;br \\\/&gt;Important material-related topics include, for example, identity testing and characterization of the plastics used, as well as the investigation of material-related damage cases.&lt;\\\/p&gt;\\n&lt;p&gt;Analytik Service Obernburg possesses many years of expertise and a broad spectrum of methods for physical and chemical testing.&lt;br \\\/&gt;With problem-adapted microscopic, spectroscopic, mechanical, or thermoanalytical investigations \\u2013 possibly also in suitable combination \\u2013 a clarification of the respective issue can be achieved quickly and cost-effectively.&lt;br \\\/&gt;Three typical examples are presented below.&lt;\\\/p&gt;\\n&lt;h5&gt;Industries &amp; Applications&lt;\\\/h5&gt;\\n&lt;p&gt;&lt;strong&gt;Medical Technology&lt;\\\/strong&gt; \\u2013 Analysis of devices, components, and materials from medical practice.&lt;\\\/p&gt;\\n&lt;h5&gt;Analysis Objectives&lt;\\\/h5&gt;\\n&lt;p&gt;Failure Analysis and Material Identification of Components and Plastics.&lt;\\\/p&gt;\\n&lt;h5&gt;Materials&lt;\\\/h5&gt;\\n&lt;p&gt;Membranes, Tubes, Injection Needles&lt;\\\/p&gt;\\n&lt;h5&gt;Analysis Methods&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Scanning Electron Microscopy (SEM-EDX)&lt;\\\/li&gt;\\n&lt;li&gt;IR Spectroscopy&lt;\\\/li&gt;\\n&lt;li&gt;ESCA \\\/ XPS&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h4&gt;Example \\u2013 Defective Capillary Membrane in a Dialyzer of a Dialysis Machine&lt;\\\/h4&gt;\\n&lt;p&gt;The filtration behavior of purchased capillary membranes was found to be faulty.&lt;br \\\/&gt;Due to the small structures of the defective hollow fiber membrane, it was examined in cross-section using scanning electron microscopy (SEM) (Fig. 2).&lt;br \\\/&gt;Large voids are visible in the membrane wall. The SEM detailed image indicates that the void is connected to the inner channel (lumen) of the capillary membrane (arrow in Fig. 2). &lt;br \\\/&gt;The large voids reduce the effectively active wall surface of the capillary membrane to up to one third of the normal value, thus representing the reason for the observed reduction in function.&lt;\\\/p&gt;\\n&lt;h4&gt;Example \\u2013 Identification Testing of Plastic Materials&lt;\\\/h4&gt;\\n&lt;p&gt;The identification of plastics used in device components such as plastic housings, membranes, or tubing systems is carried out using infrared spectroscopy (FTIR).&lt;br \\\/&gt;The signals in the FTIR spectrum (Fig. 3) can be precisely assigned to the materials used, which is crucial for failure analysis or complaint processing.&lt;br \\\/&gt;The microscopic variant of FTIR analysis is also used for identifying the smallest (from 15 \\u00b5m in size) organic particles or deposits, e.g., in tubing systems.&lt;\\\/p&gt;\\n&lt;h4&gt;Example \\u2013 Material Surfaces in Contact with Biological Media&lt;\\\/h4&gt;\\n&lt;p&gt;For material surfaces (cannulas, membranes, tubes, etc.) that come into contact with body tissue or blood, the surface-sensitive analytical method ESCA\\\/XPS (information depth of a few nm) is preferably used,&lt;br \\\/&gt;to investigate contaminations, coatings, or biocompatibility. An application example is shown in Fig. 4.&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35776\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Abb.-1-Prinzip-der-kuenstliche-Blutwaesche-Haemodialyse.jpeg\\&quot; alt=\\&quot;\\&quot; width=\\&quot;463\\&quot; height=\\&quot;273\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p&gt;Fig. 1 \\u2013 Principle of Artificial Blood Purification (Hemodialysis) &lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35777\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Abb.-2-REM-Querschnittsaufnahme-des-Schadensbereichs.jpeg\\&quot; alt=\\&quot;\\&quot; width=\\&quot;603\\&quot; height=\\&quot;452\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p&gt;Fig. 2 \\u2013 SEM Cross-sectional View of the Damaged Area &lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35778\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/FTIP-Spektrum.jpeg\\&quot; alt=\\&quot;Fig. 3: FTIR spectrum of polycarbonate (PC), a material frequently used for transparent housing parts\\&quot; width=\\&quot;784\\&quot; height=\\&quot;449\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p class=\\&quot;p1\\&quot;&gt;Fig. 3: FTIR spectrum of polycarbonate (PC), a material frequently used for transparent housing parts &lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35779\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Spitze-einer-Hohlkanuele.jpeg\\&quot; alt=\\&quot;Fig. 4: Tip of a hollow cannula and the element concentrations found with ESCA in the uppermost nanometers of the cannula&#039;s outer surface, indicating a silicone layer\\&quot; width=\\&quot;723\\&quot; height=\\&quot;386\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p class=\\&quot;p1\\&quot;&gt;Fig. 4: Tip of a hollow cannula and the element concentrations found with ESCA in the uppermost nanometers of the cannula&#039;s outer surface, indicating a silicone layer &lt;\\\/p&gt;\\n&quot;,&quot;item_icon&quot;:{&quot;value&quot;:&quot;far fa-file-pdf&quot;,&quot;library&quot;:&quot;fa-regular&quot;},&quot;_id&quot;:&quot;e13017b&quot;,&quot;content_type&quot;:&quot;toggle-content&quot;,&quot;saved_section&quot;:null,&quot;saved_template&quot;:null,&quot;toggle_custom_id&quot;:&quot;&quot;},{&quot;toggle_title&quot;:&quot;Molecular Weight Distribution&quot;,&quot;toggle_content&quot;:&quot;&lt;h4&gt;Polymer Characterization Using GPC \\u2013 Quality Testing for Plastics&lt;\\\/h4&gt;\\n&lt;h5&gt;Problem Statement&lt;\\\/h5&gt;\\n&lt;p&gt;Even if polymers are composed of the same monomers, their properties can differ. The polymer chains of a material exhibit varying chain lengths or masses. The resulting mass distribution has a decisive influence on the properties of the final plastic.&lt;br \\\/&gt;Conscious or unconscious deviations in the manufacturing procedure can thus lead to undesirable changes and result in processing difficulties or quality defects.&lt;br \\\/&gt;Unsuitable parameters of molding processes can also lead to thermal degradation and thus to a decrease in chain lengths in the product.  &lt;\\\/p&gt;\\n&lt;h5&gt;Solution&lt;\\\/h5&gt;\\n&lt;p&gt;Analytik Service Obernburg offers polymer analyses using GPC (Gel Permeation Chromatography).&lt;br \\\/&gt;In this technique, a sample of the test material is dissolved in a solvent, applied to a separation column, and pumped towards the detector.&lt;br \\\/&gt;The sample molecules are retained to varying degrees depending on their size (more precisely: their hydrodynamic volume) by a special separation material, thus reaching the detector at different times.&lt;\\\/p&gt;\\n&lt;h5&gt;Industries &amp; Applications&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Chemical Companies&lt;\\\/li&gt;\\n&lt;li&gt;Plastics Processors&lt;\\\/li&gt;\\n&lt;li&gt;Medical Technology&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Analysis Objectives&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Assessment of Product Quality&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Materials&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Polymers&lt;\\\/li&gt;\\n&lt;li&gt;Polymers&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Analysis Methods&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Gel Permeation Chromatography (GPC)&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Related Issues&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Release Tests&lt;\\\/li&gt;\\n&lt;li&gt;Oligomer Content&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Solution&lt;\\\/h5&gt;\\n&lt;p&gt;With the help of suitable reference materials of known molecular size, the average molar mass for the sample is finally obtained. This can be calculated in different ways (Mn, Mw, Mz) and thus provides several statistical parameters for production control.&lt;br \\\/&gt;Furthermore, the polydispersity D, which describes the width of the molar mass distribution, is determined. By comparing these parameters for two batches of a product, deviations and process errors can be quickly identified if necessary.  &lt;\\\/p&gt;\\n&lt;h5&gt;Advantages&lt;\\\/h5&gt;\\n&lt;p&gt;At Analytik Service Obernburg, the most common THF-soluble polymers can be analyzed (including PMMA, PS, PC, SAN).&lt;br \\\/&gt;This simple procedure provides timely and meaningful values for quality control or product development.&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35780\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/ACRYLAT-KOMPONENTE.jpeg\\&quot; alt=\\&quot;Fig. 1:&lt;\\\/strong&gt; Acrylate component of an embedding medium. Among other things, the final hardness is influenced by the average molar mass of the polymer.\\&quot; width=\\&quot;415\\&quot; height=\\&quot;313\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p class=\\&quot;p1\\&quot;&gt;&lt;strong&gt;Fig. 1:&lt;\\\/strong&gt; Acrylate component of an embedding medium. Among other things, the final hardness is influenced by the average molar mass of the polymer.&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35781\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/SCHEMATISCHE-DARSTELLUNG-DER-MOLEKUeLTRENNUNG.jpeg\\&quot; alt=\\&quot;Fig. 2: Schematic representation of molecular separation (left) and example of a detector signal for a SAN sample (right)\\&quot; width=\\&quot;965\\&quot; height=\\&quot;433\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p&gt;&lt;strong&gt;Fig. 2:&lt;\\\/strong&gt; Schematic representation of molecular separation (left) and example of a detector signal for a SAN sample (right)&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35782\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/1b35f835-11e2-476e-ba14-b5670186b5f7.jpeg\\&quot; alt=\\&quot;Fig. 3: GPC system; left: oven containing the separation column(s); center: autosampler and detector; right: pump and solvent reservoir with degassing unit.\\&quot; width=\\&quot;718\\&quot; height=\\&quot;390\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p class=\\&quot;p1\\&quot;&gt;&lt;strong&gt;Fig. 3:&lt;\\\/strong&gt; GPC system; left: oven containing the separation column(s); center: autosampler and detector; right: pump and solvent reservoir with degassing unit.&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35783\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Diagramm-der-molmassenvereilung.jpeg\\&quot; alt=\\&quot;Fig. 4: Diagram of the molar mass distribution of a SAN sample, as well as the most important determined molar masses and the polydispersity D.\\&quot; width=\\&quot;918\\&quot; height=\\&quot;409\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p class=\\&quot;p1\\&quot;&gt;&lt;strong&gt;Fig. 4:&lt;\\\/strong&gt; Diagram of the molar mass distribution of a SAN sample, as well as the most important determined molar masses and the polydispersity D.&lt;\\\/p&gt;\\n&quot;,&quot;item_icon&quot;:{&quot;value&quot;:&quot;far fa-file-pdf&quot;,&quot;library&quot;:&quot;fa-regular&quot;},&quot;_id&quot;:&quot;2aace5e&quot;,&quot;content_type&quot;:&quot;toggle-content&quot;,&quot;saved_section&quot;:null,&quot;saved_template&quot;:null,&quot;toggle_custom_id&quot;:&quot;&quot;},{&quot;toggle_title&quot;:&quot;Phase Purity with X-ray Diffraction&quot;,&quot;toggle_content&quot;:&quot;&lt;h4&gt;X-ray Diffraction \\u2013 Purity Analysis of Bone Substitutes&lt;\\\/h4&gt;\\n&lt;h5&gt;Problem Statement&lt;\\\/h5&gt;\\n&lt;p&gt;The mineral hydroxylapatite \\u2013 Ca5(OH)(PO4)3 \\u2013 is a main component of human bone substance and has proven itself as an implant material for surgical applications.&lt;br \\\/&gt;Calcium compounds exist with a similar chemical composition but with a different crystal structure and consequently altered or undesirable properties regarding biocompatibility or resorption rate.&lt;\\\/p&gt;\\n&lt;h5&gt;Solution&lt;\\\/h5&gt;\\n&lt;p&gt;X-ray diffraction allows the identification and quantitative detection of foreign phases.&lt;br \\\/&gt;For the example shown in Figure 1, the hydroxylapatite contains traces of calcium oxide (marked by reflections with arrows).&lt;br \\\/&gt;The method is described in standard ISO 13779-3.&lt;br \\\/&gt;Another important property that can be determined by X-ray diffraction is the degree of crystallinity of the sample.&lt;br \\\/&gt;Amorphous components demonstrably have higher solubility and can be resorbed more quickly in the body.&lt;br \\\/&gt;An evaluation of the peak width in the diffraction pattern allows conclusions about crystallite size.&lt;br \\\/&gt;The size and shape of hydroxylapatite crystals (HA) are additionally investigated using electron microscopy (see Fig. 2).&lt;\\\/p&gt;\\n&lt;h5&gt;Industries &amp; Applications&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Medical Technology&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Objectives&lt;\\\/h5&gt;\\n&lt;p&gt;Product Development, Quality Assurance, Failure Analysis&lt;\\\/p&gt;\\n&lt;h5&gt;Materials&lt;\\\/h5&gt;\\n&lt;p&gt;Crystalline Solids, Bone Cements&lt;\\\/p&gt;\\n&lt;h5&gt;Analysis Methods&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;X-ray Diffractometry (XRD)&lt;\\\/li&gt;\\n&lt;li&gt;Wide-Angle X-ray Scattering (WAXS)&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Complementary Methods&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;X-ray Fluorescence (XRF)&lt;\\\/li&gt;\\n&lt;li&gt;Electron Microscopy&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Advantages&lt;\\\/h5&gt;\\n&lt;p&gt;X-ray diffraction allows statements regarding phase purity, crystallinity, and crystallite size. These are parameters that must be checked for quality assurance according to standards. In addition to the application example from medical technology, this technique can also distinguish various modifications of the white pigment titanium dioxide or various calcium sulfates (gypsum, bassanite, anhydrite, etc.). For the analysis of hydroxylapatite, Analytik Service Obernburg GmbH also offers the possibility to analyze the Ca:P ratio and heavy metal freedom by X-ray fluorescence (XRF). The ICP-OES method allows the analysis of heavy metal impurities even in the lowest concentrations.    &lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35785\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Beugungsdiagramm-einer-Pulverprobe.jpeg\\&quot; alt=\\&quot;Figure 1: Diffraction pattern of a powder sample plotted as intensity versus diffraction angle (blue line, top). For comparison, below are reflection positions and intensities from a database for hydroxylapatite (green) and calcium oxide (red).\\&quot; width=\\&quot;758\\&quot; height=\\&quot;544\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p&gt;&lt;strong&gt;Figure 1:&lt;\\\/strong&gt; Diffraction pattern of a powder sample plotted as intensity versus diffraction angle (blue line, top). For comparison, below are reflection positions and intensities from a database for hydroxylapatite (green) and calcium oxide (red). &lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35784\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Visualisierung-der-Nadelstruktur.jpeg\\&quot; alt=\\&quot;Figure 2: Visualization of the needle structure and size of hydroxylapatite crystals using transmission electron microscopy.\\&quot; width=\\&quot;885\\&quot; height=\\&quot;620\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p&gt;&lt;strong&gt;Figure 2:&lt;\\\/strong&gt; Visualization of the needle structure and size of hydroxylapatite crystals using transmission electron microscopy.&lt;\\\/p&gt;\\n&quot;,&quot;item_icon&quot;:{&quot;value&quot;:&quot;far fa-file-pdf&quot;,&quot;library&quot;:&quot;fa-regular&quot;},&quot;_id&quot;:&quot;1281150&quot;,&quot;content_type&quot;:&quot;toggle-content&quot;,&quot;saved_section&quot;:null,&quot;saved_template&quot;:null,&quot;toggle_custom_id&quot;:&quot;&quot;},{&quot;toggle_title&quot;:&quot;Particle Size Analysis PMMA&quot;,&quot;toggle_content&quot;:&quot;&lt;h4&gt;Particle Analysis \\u2013 Characterization of Powders and Suspensions&lt;\\\/h4&gt;\\n&lt;h5&gt;Problem Statement&lt;\\\/h5&gt;\\n&lt;p&gt;The processing properties of a powder or suspension critically depend on the particle size, particle shape, and surface chemistry of the particles. Thus, one powder may flow finely, while another tends to clump. Particles that are too large can clog filters, while particles that are too small can cause significant dust formation during further processing. This is just a small selection of issues attributable to different particle properties.   &lt;\\\/p&gt;\\n&lt;h5&gt;Solution&lt;\\\/h5&gt;\\n&lt;p&gt;At Analytik Service Obernburg, various analytical methods are used for particle characterization, which will be discussed in more detail below.&lt;\\\/p&gt;\\n&lt;h5&gt;Industries &amp; Applications&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Medical Technology&lt;\\\/li&gt;\\n&lt;li&gt;Paint Manufacturers&lt;\\\/li&gt;\\n&lt;li&gt;Compounders&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Analysis Objectives&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Determination of Particle Size&lt;\\\/li&gt;\\n&lt;li&gt;Assessment of Particle Shape&lt;\\\/li&gt;\\n&lt;li&gt;Investigation of Agglomeration Tendency&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Materials&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Powders&lt;\\\/li&gt;\\n&lt;li&gt;Suspensions&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Analysis Methods&lt;\\\/h5&gt;\\n&lt;ul&gt;\\n&lt;li&gt;Laser Diffraction&lt;\\\/li&gt;\\n&lt;li&gt;Scanning Electron Microscopy (SEM-EDX)&lt;\\\/li&gt;\\n&lt;\\\/ul&gt;\\n&lt;h5&gt;Example \\u2013 Particle Size Distribution&lt;\\\/h5&gt;\\n&lt;p&gt;The determination of particle size distribution is carried out using laser diffraction. Particles between 0.1 \\u00b5m and 2000 \\u00b5m can be measured. A distribution curve is obtained, from which the particle size can be read, as well as various statistical values describing the distribution (Fig. 1). These values can be directly used for validating the manufacturing process in quality assurance. The test is performed on the powder dispersed in water. By measuring with and without ultrasound, a distinction can be made between agglomerates and primary particles.     &lt;\\\/p&gt;\\n&lt;h5&gt;Example \\u2013 Particle Shape&lt;\\\/h5&gt;\\n&lt;p&gt;Various microscopic measurement methods are available for investigating particle shape \\u2013 from light microscopy to electron microscopy (SEM) and atomic force microscopy (AFM). These methods allow not only the characterization of the particle&#039;s shape but also its surface fine structure. Both are crucial for the interaction between particles (e.g., agglomeration tendency) (Fig. 2). If required, the particle shape can be quantified by subsequent computer image analysis.   &lt;\\\/p&gt;\\n&lt;h5&gt;Example \\u2013 Surface Chemistry&lt;\\\/h5&gt;\\n&lt;p&gt;Just as particle shape influences the properties during processing or the distribution of particles in the final product, so does surface chemistry (moisture, foreign substances like oils, or targeted surface modifications). Depending on the specific question, different chemical or spectroscopic methods are used here to detect changes in surface chemistry. &lt;\\\/p&gt;\\n&lt;h5&gt;Advantages&lt;\\\/h5&gt;\\n&lt;p&gt;The described methods allow for comprehensive characterization and visualization of particles in powders or suspensions. This enables the analysis of raw materials or products within the scope of quality assurance. The methods are also suitable for determining the cause of problems (e.g., during processing) in case of damage. Furthermore, Analytik Service Obernburg possesses extensive expertise for the analysis of catalysts or fillers in solids.   &lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35786\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Partikelgroessenverteilung-zweier-Proben.jpeg\\&quot; alt=\\&quot;Fig. 1: Particle size distribution of two samples from different production batches.\\&quot; width=\\&quot;796\\&quot; height=\\&quot;292\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p class=\\&quot;p1\\&quot;&gt;&lt;strong&gt;Fig. 1:&lt;\\\/strong&gt;  Particle size distribution of two samples from different production batches.&lt;\\\/p&gt;\\n&lt;p&gt;&lt;img class=\\&quot;alignnone size-full wp-image-35787\\&quot; src=\\&quot;https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Vergleich-von-Pulvern.jpeg\\&quot; alt=\\&quot;Fig. 2: Comparison of powders with different agglomeration tendencies.\\&quot; width=\\&quot;790\\&quot; height=\\&quot;331\\&quot;&gt;&lt;\\\/p&gt;\\n&lt;p class=\\&quot;p1\\&quot;&gt;&lt;strong&gt;Fig. 2:&lt;\\\/strong&gt;  Comparison of powders with different agglomeration tendencies&lt;\\\/p&gt;\\n&quot;,&quot;item_icon&quot;:{&quot;value&quot;:&quot;far fa-file-pdf&quot;,&quot;library&quot;:&quot;fa-regular&quot;},&quot;_id&quot;:&quot;f977db4&quot;,&quot;content_type&quot;:&quot;toggle-content&quot;,&quot;saved_section&quot;:null,&quot;saved_template&quot;:null,&quot;toggle_custom_id&quot;:&quot;&quot;}],&quot;type&quot;:&quot;accordion&quot;}\" data-widget_type=\"cmsmasters-toggles.default\">\n\t\t\t\t\t<div class=\"elementor-widget-cmsmasters-toggles__list\"><div class=\"elementor-widget-cmsmasters-toggles__item\"><h3 id=\"elementor-tab-title-7241\" class=\"elementor-widget-cmsmasters-toggles__title\" data-tab=\"1\" aria-expanded=\"false\" aria-controls=\"elementor-widget-cmsmasters-toggles__content-7241\" tabindex=\"0\"><a class=\"elementor-widget-cmsmasters-toggles__title-link cmsmasters_enable_trigger_icon\" href=\"#\" tabindex=\"-1\"><span class=\"elementor-widget-cmsmasters-toggles__item-icon\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-file-pdf\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M369.9 97.9L286 14C277 5 264.8-.1 252.1-.1H48C21.5 0 0 21.5 0 48v416c0 26.5 21.5 48 48 48h288c26.5 0 48-21.5 48-48V131.9c0-12.7-5.1-25-14.1-34zM332.1 128H256V51.9l76.1 76.1zM48 464V48h160v104c0 13.3 10.7 24 24 24h104v288H48zm250.2-143.7c-12.2-12-47-8.7-64.4-6.5-17.2-10.5-28.7-25-36.8-46.3 3.9-16.1 10.1-40.6 5.4-56-4.2-26.2-37.8-23.6-42.6-5.9-4.4 16.1-.4 38.5 7 67.1-10 23.9-24.9 56-35.4 74.4-20 10.3-47 26.2-51 46.2-3.3 15.8 26 55.2 76.1-31.2 22.4-7.4 46.8-16.5 68.4-20.1 18.9 10.2 41 17 55.8 17 25.5 0 28-28.2 17.5-38.7zm-198.1 77.8c5.1-13.7 24.5-29.5 30.4-35-19 30.3-30.4 35.7-30.4 35zm81.6-190.6c7.4 0 6.7 32.1 1.8 40.8-4.4-13.9-4.3-40.8-1.8-40.8zm-24.4 136.6c9.7-16.9 18-37 24.7-54.7 8.3 15.1 18.9 27.2 30.1 35.5-20.8 4.3-38.9 13.1-54.8 19.2zm131.6-5s-5 6-37.3-7.8c35.1-2.6 40.9 5.4 37.3 7.8z\"><\/path><\/svg><\/span><span class=\"elementor-widget-cmsmasters-toggles__title-text\">Material Identification with NMR<\/span><\/a><span class=\"elementor-widget-cmsmasters-toggles__trigger\"><span class=\"elementor-widget-cmsmasters-toggles__trigger-closed\"><i aria-hidden=\"true\" aria-label=\"Closed\" class=\"cmsmsdemo-icon- cmsms-demo-icon-plus\"><\/i><\/span><span class=\"elementor-widget-cmsmasters-toggles__trigger-opened\"><i aria-hidden=\"true\" aria-label=\"Opened\" class=\"cmsmsdemo-icon- cmsms-demo-icon-minus\"><\/i><\/span><\/span><\/h3><div id=\"elementor-widget-cmsmasters-toggles__content-7241\" class=\"elementor-widget-cmsmasters-toggles__content elementor-clearfix\" data-tab=\"1\"><h4>Material Identification in Medical Technology<\/h4>\n<h5>Problem Statement<\/h5>\n<p>The characterization of medical devices or their underlying raw materials often requires the use of a broad spectrum of analytical and physical methods. This involves a significant time commitment.<br \/>However, in many cases, quick material information is needed first, which is then refined later with further analyses. <\/p>\n<h5>Solution<\/h5>\n<p>A versatile method for quickly gaining an overview of a medical device is high-resolution NMR spectroscopy.<br \/>It is a method for detailed structural elucidation and quantification of organic substances.<br \/>NMR spectroscopy is applicable to all types of organic compounds, including polymers.<br \/>Mixtures can be quantified and impurities detected.<\/p>\n<h5>Industries &amp; Applications<\/h5>\n<p><strong>Medical Technology<\/strong> \u2013 Identification of materials and impurities in complex product structures.<\/p>\n<h5>Analysis Objectives<\/h5>\n<p>Rapid material overview for complex matrices for targeted selection of further test procedures.<\/p>\n<h5>Materials<\/h5>\n<p>Composite Materials, Product Formulations<\/p>\n<h5>Analysis Methods<\/h5>\n<ul>\n<li>\u00b9H-NMR (Nuclear Magnetic Resonance)<\/li>\n<\/ul>\n<h5>Complementary Methods<\/h5>\n<ul>\n<li>Extraction<\/li>\n<\/ul>\n<h5>Related Issues<\/h5>\n<ul>\n<li>Purity Determinations<\/li>\n<li>Release Analytics<\/li>\n<\/ul>\n<h4>Example \u2013 Heat Patch<\/h4>\n<p>In a commercially available heat patch, the active ingredient <strong>Nonivamide<\/strong> is detectable in the spectrum after simple extraction with dichloromethane.<br \/>However, further information on the carrier liquid <strong>(1,2-propanediol)<\/strong>,<br \/>preservative <strong>(4-hydroxybenzoate)<\/strong>, adhesive <strong>(acrylate)<\/strong>, and fabric material <strong>(polyester)<\/strong> can also be read from the spectrum.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35774\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/beispiel-WAeRMEPFLASTER.jpeg\" alt=\"\" width=\"448\" height=\"301\"><\/p>\n<h4>Example \u2013 Warming Ointment<\/h4>\n<p>In comparison, a spectrum excerpt (only the aromatic region) of the CDCl\u2083 extract of a warming ointment is shown.<br \/>Even without prior processing of the ointment material, the active ingredients <strong>Nicoboxil<\/strong> and <strong>Nonivamide<\/strong><br \/>can be identified and approximately quantified despite the presence of the ointment base.<\/p>\n<p>The quantitative ratio of Nicoboxil to Nonivamide is determined from this spectrum to be approximately <strong>91:9<\/strong>,<br \/>the package insert for the warming ointment states <strong>86:14<\/strong>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35775\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/beispiel-waermesalbe.jpeg\" alt=\"\" width=\"461\" height=\"361\"><\/p>\n<\/div><\/div><div class=\"elementor-widget-cmsmasters-toggles__item\"><h3 id=\"elementor-tab-title-7242\" class=\"elementor-widget-cmsmasters-toggles__title\" data-tab=\"2\" aria-expanded=\"false\" aria-controls=\"elementor-widget-cmsmasters-toggles__content-7242\" tabindex=\"0\"><a class=\"elementor-widget-cmsmasters-toggles__title-link cmsmasters_enable_trigger_icon\" href=\"#\" tabindex=\"-1\"><span class=\"elementor-widget-cmsmasters-toggles__item-icon\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-file-pdf\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M369.9 97.9L286 14C277 5 264.8-.1 252.1-.1H48C21.5 0 0 21.5 0 48v416c0 26.5 21.5 48 48 48h288c26.5 0 48-21.5 48-48V131.9c0-12.7-5.1-25-14.1-34zM332.1 128H256V51.9l76.1 76.1zM48 464V48h160v104c0 13.3 10.7 24 24 24h104v288H48zm250.2-143.7c-12.2-12-47-8.7-64.4-6.5-17.2-10.5-28.7-25-36.8-46.3 3.9-16.1 10.1-40.6 5.4-56-4.2-26.2-37.8-23.6-42.6-5.9-4.4 16.1-.4 38.5 7 67.1-10 23.9-24.9 56-35.4 74.4-20 10.3-47 26.2-51 46.2-3.3 15.8 26 55.2 76.1-31.2 22.4-7.4 46.8-16.5 68.4-20.1 18.9 10.2 41 17 55.8 17 25.5 0 28-28.2 17.5-38.7zm-198.1 77.8c5.1-13.7 24.5-29.5 30.4-35-19 30.3-30.4 35.7-30.4 35zm81.6-190.6c7.4 0 6.7 32.1 1.8 40.8-4.4-13.9-4.3-40.8-1.8-40.8zm-24.4 136.6c9.7-16.9 18-37 24.7-54.7 8.3 15.1 18.9 27.2 30.1 35.5-20.8 4.3-38.9 13.1-54.8 19.2zm131.6-5s-5 6-37.3-7.8c35.1-2.6 40.9 5.4 37.3 7.8z\"><\/path><\/svg><\/span><span class=\"elementor-widget-cmsmasters-toggles__title-text\">Analytics in Medical Technology<\/span><\/a><span class=\"elementor-widget-cmsmasters-toggles__trigger\"><span class=\"elementor-widget-cmsmasters-toggles__trigger-closed\"><i aria-hidden=\"true\" aria-label=\"Closed\" class=\"cmsmsdemo-icon- cmsms-demo-icon-plus\"><\/i><\/span><span class=\"elementor-widget-cmsmasters-toggles__trigger-opened\"><i aria-hidden=\"true\" aria-label=\"Opened\" class=\"cmsmsdemo-icon- cmsms-demo-icon-minus\"><\/i><\/span><\/span><\/h3><div id=\"elementor-widget-cmsmasters-toggles__content-7242\" class=\"elementor-widget-cmsmasters-toggles__content elementor-clearfix\" data-tab=\"2\"><h4>Medical Technology<\/h4>\n<p>Medical technology involves the interaction of materials science disciplines with medicine and pharmacy.<br \/>Only through this connection is the development and application of complex medical devices possible.<\/p>\n<p>An example of this is artificial blood purification using hemodialysis. Here \u2013 as shown in Fig. 1 \u2013 a patient&#8217;s blood is passed through a dialyzer outside their body and then returned.<br \/>In the dialyzer, toxins are filtered out of the blood through small pores, while vital components remain in the blood.<br \/>Further components of a dialysis machine include the blood pump, tubing systems, and measurement and monitoring devices. Additionally, a medication that acts as an anticoagulant can be administered via the dialysis machine.   <\/p>\n<p>The various components used here must meet high material-technical and medical requirements.<br \/>Important material-related topics include, for example, identity testing and characterization of the plastics used, as well as the investigation of material-related damage cases.<\/p>\n<p>Analytik Service Obernburg possesses many years of expertise and a broad spectrum of methods for physical and chemical testing.<br \/>With problem-adapted microscopic, spectroscopic, mechanical, or thermoanalytical investigations \u2013 possibly also in suitable combination \u2013 a clarification of the respective issue can be achieved quickly and cost-effectively.<br \/>Three typical examples are presented below.<\/p>\n<h5>Industries &amp; Applications<\/h5>\n<p><strong>Medical Technology<\/strong> \u2013 Analysis of devices, components, and materials from medical practice.<\/p>\n<h5>Analysis Objectives<\/h5>\n<p>Failure Analysis and Material Identification of Components and Plastics.<\/p>\n<h5>Materials<\/h5>\n<p>Membranes, Tubes, Injection Needles<\/p>\n<h5>Analysis Methods<\/h5>\n<ul>\n<li>Scanning Electron Microscopy (SEM-EDX)<\/li>\n<li>IR Spectroscopy<\/li>\n<li>ESCA \/ XPS<\/li>\n<\/ul>\n<h4>Example \u2013 Defective Capillary Membrane in a Dialyzer of a Dialysis Machine<\/h4>\n<p>The filtration behavior of purchased capillary membranes was found to be faulty.<br \/>Due to the small structures of the defective hollow fiber membrane, it was examined in cross-section using scanning electron microscopy (SEM) (Fig. 2).<br \/>Large voids are visible in the membrane wall. The SEM detailed image indicates that the void is connected to the inner channel (lumen) of the capillary membrane (arrow in Fig. 2). <br \/>The large voids reduce the effectively active wall surface of the capillary membrane to up to one third of the normal value, thus representing the reason for the observed reduction in function.<\/p>\n<h4>Example \u2013 Identification Testing of Plastic Materials<\/h4>\n<p>The identification of plastics used in device components such as plastic housings, membranes, or tubing systems is carried out using infrared spectroscopy (FTIR).<br \/>The signals in the FTIR spectrum (Fig. 3) can be precisely assigned to the materials used, which is crucial for failure analysis or complaint processing.<br \/>The microscopic variant of FTIR analysis is also used for identifying the smallest (from 15 \u00b5m in size) organic particles or deposits, e.g., in tubing systems.<\/p>\n<h4>Example \u2013 Material Surfaces in Contact with Biological Media<\/h4>\n<p>For material surfaces (cannulas, membranes, tubes, etc.) that come into contact with body tissue or blood, the surface-sensitive analytical method ESCA\/XPS (information depth of a few nm) is preferably used,<br \/>to investigate contaminations, coatings, or biocompatibility. An application example is shown in Fig. 4.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35776\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Abb.-1-Prinzip-der-kuenstliche-Blutwaesche-Haemodialyse.jpeg\" alt=\"\" width=\"463\" height=\"273\"><\/p>\n<p>Fig. 1 \u2013 Principle of Artificial Blood Purification (Hemodialysis) <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35777\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Abb.-2-REM-Querschnittsaufnahme-des-Schadensbereichs.jpeg\" alt=\"\" width=\"603\" height=\"452\"><\/p>\n<p>Fig. 2 \u2013 SEM Cross-sectional View of the Damaged Area <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35778\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/FTIP-Spektrum.jpeg\" alt=\"Fig. 3: FTIR spectrum of polycarbonate (PC), a material frequently used for transparent housing parts\" width=\"784\" height=\"449\"><\/p>\n<p class=\"p1\">Fig. 3: FTIR spectrum of polycarbonate (PC), a material frequently used for transparent housing parts <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35779\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Spitze-einer-Hohlkanuele.jpeg\" alt=\"Fig. 4: Tip of a hollow cannula and the element concentrations found with ESCA in the uppermost nanometers of the cannula's outer surface, indicating a silicone layer\" width=\"723\" height=\"386\"><\/p>\n<p class=\"p1\">Fig. 4: Tip of a hollow cannula and the element concentrations found with ESCA in the uppermost nanometers of the cannula&#8217;s outer surface, indicating a silicone layer <\/p>\n<\/div><\/div><div class=\"elementor-widget-cmsmasters-toggles__item\"><h3 id=\"elementor-tab-title-7243\" class=\"elementor-widget-cmsmasters-toggles__title\" data-tab=\"3\" aria-expanded=\"false\" aria-controls=\"elementor-widget-cmsmasters-toggles__content-7243\" tabindex=\"0\"><a class=\"elementor-widget-cmsmasters-toggles__title-link cmsmasters_enable_trigger_icon\" href=\"#\" tabindex=\"-1\"><span class=\"elementor-widget-cmsmasters-toggles__item-icon\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-file-pdf\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M369.9 97.9L286 14C277 5 264.8-.1 252.1-.1H48C21.5 0 0 21.5 0 48v416c0 26.5 21.5 48 48 48h288c26.5 0 48-21.5 48-48V131.9c0-12.7-5.1-25-14.1-34zM332.1 128H256V51.9l76.1 76.1zM48 464V48h160v104c0 13.3 10.7 24 24 24h104v288H48zm250.2-143.7c-12.2-12-47-8.7-64.4-6.5-17.2-10.5-28.7-25-36.8-46.3 3.9-16.1 10.1-40.6 5.4-56-4.2-26.2-37.8-23.6-42.6-5.9-4.4 16.1-.4 38.5 7 67.1-10 23.9-24.9 56-35.4 74.4-20 10.3-47 26.2-51 46.2-3.3 15.8 26 55.2 76.1-31.2 22.4-7.4 46.8-16.5 68.4-20.1 18.9 10.2 41 17 55.8 17 25.5 0 28-28.2 17.5-38.7zm-198.1 77.8c5.1-13.7 24.5-29.5 30.4-35-19 30.3-30.4 35.7-30.4 35zm81.6-190.6c7.4 0 6.7 32.1 1.8 40.8-4.4-13.9-4.3-40.8-1.8-40.8zm-24.4 136.6c9.7-16.9 18-37 24.7-54.7 8.3 15.1 18.9 27.2 30.1 35.5-20.8 4.3-38.9 13.1-54.8 19.2zm131.6-5s-5 6-37.3-7.8c35.1-2.6 40.9 5.4 37.3 7.8z\"><\/path><\/svg><\/span><span class=\"elementor-widget-cmsmasters-toggles__title-text\">Molecular Weight Distribution<\/span><\/a><span class=\"elementor-widget-cmsmasters-toggles__trigger\"><span class=\"elementor-widget-cmsmasters-toggles__trigger-closed\"><i aria-hidden=\"true\" aria-label=\"Closed\" class=\"cmsmsdemo-icon- cmsms-demo-icon-plus\"><\/i><\/span><span class=\"elementor-widget-cmsmasters-toggles__trigger-opened\"><i aria-hidden=\"true\" aria-label=\"Opened\" class=\"cmsmsdemo-icon- cmsms-demo-icon-minus\"><\/i><\/span><\/span><\/h3><div id=\"elementor-widget-cmsmasters-toggles__content-7243\" class=\"elementor-widget-cmsmasters-toggles__content elementor-clearfix\" data-tab=\"3\"><h4>Polymer Characterization Using GPC \u2013 Quality Testing for Plastics<\/h4>\n<h5>Problem Statement<\/h5>\n<p>Even if polymers are composed of the same monomers, their properties can differ. The polymer chains of a material exhibit varying chain lengths or masses. The resulting mass distribution has a decisive influence on the properties of the final plastic.<br \/>Conscious or unconscious deviations in the manufacturing procedure can thus lead to undesirable changes and result in processing difficulties or quality defects.<br \/>Unsuitable parameters of molding processes can also lead to thermal degradation and thus to a decrease in chain lengths in the product.  <\/p>\n<h5>Solution<\/h5>\n<p>Analytik Service Obernburg offers polymer analyses using GPC (Gel Permeation Chromatography).<br \/>In this technique, a sample of the test material is dissolved in a solvent, applied to a separation column, and pumped towards the detector.<br \/>The sample molecules are retained to varying degrees depending on their size (more precisely: their hydrodynamic volume) by a special separation material, thus reaching the detector at different times.<\/p>\n<h5>Industries &amp; Applications<\/h5>\n<ul>\n<li>Chemical Companies<\/li>\n<li>Plastics Processors<\/li>\n<li>Medical Technology<\/li>\n<\/ul>\n<h5>Analysis Objectives<\/h5>\n<ul>\n<li>Assessment of Product Quality<\/li>\n<\/ul>\n<h5>Materials<\/h5>\n<ul>\n<li>Polymers<\/li>\n<li>Polymers<\/li>\n<\/ul>\n<h5>Analysis Methods<\/h5>\n<ul>\n<li>Gel Permeation Chromatography (GPC)<\/li>\n<\/ul>\n<h5>Related Issues<\/h5>\n<ul>\n<li>Release Tests<\/li>\n<li>Oligomer Content<\/li>\n<\/ul>\n<h5>Solution<\/h5>\n<p>With the help of suitable reference materials of known molecular size, the average molar mass for the sample is finally obtained. This can be calculated in different ways (Mn, Mw, Mz) and thus provides several statistical parameters for production control.<br \/>Furthermore, the polydispersity D, which describes the width of the molar mass distribution, is determined. By comparing these parameters for two batches of a product, deviations and process errors can be quickly identified if necessary.  <\/p>\n<h5>Advantages<\/h5>\n<p>At Analytik Service Obernburg, the most common THF-soluble polymers can be analyzed (including PMMA, PS, PC, SAN).<br \/>This simple procedure provides timely and meaningful values for quality control or product development.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35780\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/ACRYLAT-KOMPONENTE.jpeg\" alt=\"Fig. 1:&lt;\/strong&gt; Acrylate component of an embedding medium. Among other things, the final hardness is influenced by the average molar mass of the polymer.\" width=\"415\" height=\"313\"><\/p>\n<p class=\"p1\"><strong>Fig. 1:<\/strong> Acrylate component of an embedding medium. Among other things, the final hardness is influenced by the average molar mass of the polymer.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35781\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/SCHEMATISCHE-DARSTELLUNG-DER-MOLEKUeLTRENNUNG.jpeg\" alt=\"Fig. 2: Schematic representation of molecular separation (left) and example of a detector signal for a SAN sample (right)\" width=\"965\" height=\"433\"><\/p>\n<p><strong>Fig. 2:<\/strong> Schematic representation of molecular separation (left) and example of a detector signal for a SAN sample (right)<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35782\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/1b35f835-11e2-476e-ba14-b5670186b5f7.jpeg\" alt=\"Fig. 3: GPC system; left: oven containing the separation column(s); center: autosampler and detector; right: pump and solvent reservoir with degassing unit.\" width=\"718\" height=\"390\"><\/p>\n<p class=\"p1\"><strong>Fig. 3:<\/strong> GPC system; left: oven containing the separation column(s); center: autosampler and detector; right: pump and solvent reservoir with degassing unit.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35783\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Diagramm-der-molmassenvereilung.jpeg\" alt=\"Fig. 4: Diagram of the molar mass distribution of a SAN sample, as well as the most important determined molar masses and the polydispersity D.\" width=\"918\" height=\"409\"><\/p>\n<p class=\"p1\"><strong>Fig. 4:<\/strong> Diagram of the molar mass distribution of a SAN sample, as well as the most important determined molar masses and the polydispersity D.<\/p>\n<\/div><\/div><div class=\"elementor-widget-cmsmasters-toggles__item\"><h3 id=\"elementor-tab-title-7244\" class=\"elementor-widget-cmsmasters-toggles__title\" data-tab=\"4\" aria-expanded=\"false\" aria-controls=\"elementor-widget-cmsmasters-toggles__content-7244\" tabindex=\"0\"><a class=\"elementor-widget-cmsmasters-toggles__title-link cmsmasters_enable_trigger_icon\" href=\"#\" tabindex=\"-1\"><span class=\"elementor-widget-cmsmasters-toggles__item-icon\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-file-pdf\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M369.9 97.9L286 14C277 5 264.8-.1 252.1-.1H48C21.5 0 0 21.5 0 48v416c0 26.5 21.5 48 48 48h288c26.5 0 48-21.5 48-48V131.9c0-12.7-5.1-25-14.1-34zM332.1 128H256V51.9l76.1 76.1zM48 464V48h160v104c0 13.3 10.7 24 24 24h104v288H48zm250.2-143.7c-12.2-12-47-8.7-64.4-6.5-17.2-10.5-28.7-25-36.8-46.3 3.9-16.1 10.1-40.6 5.4-56-4.2-26.2-37.8-23.6-42.6-5.9-4.4 16.1-.4 38.5 7 67.1-10 23.9-24.9 56-35.4 74.4-20 10.3-47 26.2-51 46.2-3.3 15.8 26 55.2 76.1-31.2 22.4-7.4 46.8-16.5 68.4-20.1 18.9 10.2 41 17 55.8 17 25.5 0 28-28.2 17.5-38.7zm-198.1 77.8c5.1-13.7 24.5-29.5 30.4-35-19 30.3-30.4 35.7-30.4 35zm81.6-190.6c7.4 0 6.7 32.1 1.8 40.8-4.4-13.9-4.3-40.8-1.8-40.8zm-24.4 136.6c9.7-16.9 18-37 24.7-54.7 8.3 15.1 18.9 27.2 30.1 35.5-20.8 4.3-38.9 13.1-54.8 19.2zm131.6-5s-5 6-37.3-7.8c35.1-2.6 40.9 5.4 37.3 7.8z\"><\/path><\/svg><\/span><span class=\"elementor-widget-cmsmasters-toggles__title-text\">Phase Purity with X-ray Diffraction<\/span><\/a><span class=\"elementor-widget-cmsmasters-toggles__trigger\"><span class=\"elementor-widget-cmsmasters-toggles__trigger-closed\"><i aria-hidden=\"true\" aria-label=\"Closed\" class=\"cmsmsdemo-icon- cmsms-demo-icon-plus\"><\/i><\/span><span class=\"elementor-widget-cmsmasters-toggles__trigger-opened\"><i aria-hidden=\"true\" aria-label=\"Opened\" class=\"cmsmsdemo-icon- cmsms-demo-icon-minus\"><\/i><\/span><\/span><\/h3><div id=\"elementor-widget-cmsmasters-toggles__content-7244\" class=\"elementor-widget-cmsmasters-toggles__content elementor-clearfix\" data-tab=\"4\"><h4>X-ray Diffraction \u2013 Purity Analysis of Bone Substitutes<\/h4>\n<h5>Problem Statement<\/h5>\n<p>The mineral hydroxylapatite \u2013 Ca5(OH)(PO4)3 \u2013 is a main component of human bone substance and has proven itself as an implant material for surgical applications.<br \/>Calcium compounds exist with a similar chemical composition but with a different crystal structure and consequently altered or undesirable properties regarding biocompatibility or resorption rate.<\/p>\n<h5>Solution<\/h5>\n<p>X-ray diffraction allows the identification and quantitative detection of foreign phases.<br \/>For the example shown in Figure 1, the hydroxylapatite contains traces of calcium oxide (marked by reflections with arrows).<br \/>The method is described in standard ISO 13779-3.<br \/>Another important property that can be determined by X-ray diffraction is the degree of crystallinity of the sample.<br \/>Amorphous components demonstrably have higher solubility and can be resorbed more quickly in the body.<br \/>An evaluation of the peak width in the diffraction pattern allows conclusions about crystallite size.<br \/>The size and shape of hydroxylapatite crystals (HA) are additionally investigated using electron microscopy (see Fig. 2).<\/p>\n<h5>Industries &amp; Applications<\/h5>\n<ul>\n<li>Medical Technology<\/li>\n<\/ul>\n<h5>Objectives<\/h5>\n<p>Product Development, Quality Assurance, Failure Analysis<\/p>\n<h5>Materials<\/h5>\n<p>Crystalline Solids, Bone Cements<\/p>\n<h5>Analysis Methods<\/h5>\n<ul>\n<li>X-ray Diffractometry (XRD)<\/li>\n<li>Wide-Angle X-ray Scattering (WAXS)<\/li>\n<\/ul>\n<h5>Complementary Methods<\/h5>\n<ul>\n<li>X-ray Fluorescence (XRF)<\/li>\n<li>Electron Microscopy<\/li>\n<\/ul>\n<h5>Advantages<\/h5>\n<p>X-ray diffraction allows statements regarding phase purity, crystallinity, and crystallite size. These are parameters that must be checked for quality assurance according to standards. In addition to the application example from medical technology, this technique can also distinguish various modifications of the white pigment titanium dioxide or various calcium sulfates (gypsum, bassanite, anhydrite, etc.). For the analysis of hydroxylapatite, Analytik Service Obernburg GmbH also offers the possibility to analyze the Ca:P ratio and heavy metal freedom by X-ray fluorescence (XRF). The ICP-OES method allows the analysis of heavy metal impurities even in the lowest concentrations.    <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35785\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Beugungsdiagramm-einer-Pulverprobe.jpeg\" alt=\"Figure 1: Diffraction pattern of a powder sample plotted as intensity versus diffraction angle (blue line, top). For comparison, below are reflection positions and intensities from a database for hydroxylapatite (green) and calcium oxide (red).\" width=\"758\" height=\"544\"><\/p>\n<p><strong>Figure 1:<\/strong> Diffraction pattern of a powder sample plotted as intensity versus diffraction angle (blue line, top). For comparison, below are reflection positions and intensities from a database for hydroxylapatite (green) and calcium oxide (red). <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35784\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Visualisierung-der-Nadelstruktur.jpeg\" alt=\"Figure 2: Visualization of the needle structure and size of hydroxylapatite crystals using transmission electron microscopy.\" width=\"885\" height=\"620\"><\/p>\n<p><strong>Figure 2:<\/strong> Visualization of the needle structure and size of hydroxylapatite crystals using transmission electron microscopy.<\/p>\n<\/div><\/div><div class=\"elementor-widget-cmsmasters-toggles__item\"><h3 id=\"elementor-tab-title-7245\" class=\"elementor-widget-cmsmasters-toggles__title\" data-tab=\"5\" aria-expanded=\"false\" aria-controls=\"elementor-widget-cmsmasters-toggles__content-7245\" tabindex=\"0\"><a class=\"elementor-widget-cmsmasters-toggles__title-link cmsmasters_enable_trigger_icon\" href=\"#\" tabindex=\"-1\"><span class=\"elementor-widget-cmsmasters-toggles__item-icon\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-file-pdf\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M369.9 97.9L286 14C277 5 264.8-.1 252.1-.1H48C21.5 0 0 21.5 0 48v416c0 26.5 21.5 48 48 48h288c26.5 0 48-21.5 48-48V131.9c0-12.7-5.1-25-14.1-34zM332.1 128H256V51.9l76.1 76.1zM48 464V48h160v104c0 13.3 10.7 24 24 24h104v288H48zm250.2-143.7c-12.2-12-47-8.7-64.4-6.5-17.2-10.5-28.7-25-36.8-46.3 3.9-16.1 10.1-40.6 5.4-56-4.2-26.2-37.8-23.6-42.6-5.9-4.4 16.1-.4 38.5 7 67.1-10 23.9-24.9 56-35.4 74.4-20 10.3-47 26.2-51 46.2-3.3 15.8 26 55.2 76.1-31.2 22.4-7.4 46.8-16.5 68.4-20.1 18.9 10.2 41 17 55.8 17 25.5 0 28-28.2 17.5-38.7zm-198.1 77.8c5.1-13.7 24.5-29.5 30.4-35-19 30.3-30.4 35.7-30.4 35zm81.6-190.6c7.4 0 6.7 32.1 1.8 40.8-4.4-13.9-4.3-40.8-1.8-40.8zm-24.4 136.6c9.7-16.9 18-37 24.7-54.7 8.3 15.1 18.9 27.2 30.1 35.5-20.8 4.3-38.9 13.1-54.8 19.2zm131.6-5s-5 6-37.3-7.8c35.1-2.6 40.9 5.4 37.3 7.8z\"><\/path><\/svg><\/span><span class=\"elementor-widget-cmsmasters-toggles__title-text\">Particle Size Analysis PMMA<\/span><\/a><span class=\"elementor-widget-cmsmasters-toggles__trigger\"><span class=\"elementor-widget-cmsmasters-toggles__trigger-closed\"><i aria-hidden=\"true\" aria-label=\"Closed\" class=\"cmsmsdemo-icon- cmsms-demo-icon-plus\"><\/i><\/span><span class=\"elementor-widget-cmsmasters-toggles__trigger-opened\"><i aria-hidden=\"true\" aria-label=\"Opened\" class=\"cmsmsdemo-icon- cmsms-demo-icon-minus\"><\/i><\/span><\/span><\/h3><div id=\"elementor-widget-cmsmasters-toggles__content-7245\" class=\"elementor-widget-cmsmasters-toggles__content elementor-clearfix\" data-tab=\"5\"><h4>Particle Analysis \u2013 Characterization of Powders and Suspensions<\/h4>\n<h5>Problem Statement<\/h5>\n<p>The processing properties of a powder or suspension critically depend on the particle size, particle shape, and surface chemistry of the particles. Thus, one powder may flow finely, while another tends to clump. Particles that are too large can clog filters, while particles that are too small can cause significant dust formation during further processing. This is just a small selection of issues attributable to different particle properties.   <\/p>\n<h5>Solution<\/h5>\n<p>At Analytik Service Obernburg, various analytical methods are used for particle characterization, which will be discussed in more detail below.<\/p>\n<h5>Industries &amp; Applications<\/h5>\n<ul>\n<li>Medical Technology<\/li>\n<li>Paint Manufacturers<\/li>\n<li>Compounders<\/li>\n<\/ul>\n<h5>Analysis Objectives<\/h5>\n<ul>\n<li>Determination of Particle Size<\/li>\n<li>Assessment of Particle Shape<\/li>\n<li>Investigation of Agglomeration Tendency<\/li>\n<\/ul>\n<h5>Materials<\/h5>\n<ul>\n<li>Powders<\/li>\n<li>Suspensions<\/li>\n<\/ul>\n<h5>Analysis Methods<\/h5>\n<ul>\n<li>Laser Diffraction<\/li>\n<li>Scanning Electron Microscopy (SEM-EDX)<\/li>\n<\/ul>\n<h5>Example \u2013 Particle Size Distribution<\/h5>\n<p>The determination of particle size distribution is carried out using laser diffraction. Particles between 0.1 \u00b5m and 2000 \u00b5m can be measured. A distribution curve is obtained, from which the particle size can be read, as well as various statistical values describing the distribution (Fig. 1). These values can be directly used for validating the manufacturing process in quality assurance. The test is performed on the powder dispersed in water. By measuring with and without ultrasound, a distinction can be made between agglomerates and primary particles.     <\/p>\n<h5>Example \u2013 Particle Shape<\/h5>\n<p>Various microscopic measurement methods are available for investigating particle shape \u2013 from light microscopy to electron microscopy (SEM) and atomic force microscopy (AFM). These methods allow not only the characterization of the particle&#8217;s shape but also its surface fine structure. Both are crucial for the interaction between particles (e.g., agglomeration tendency) (Fig. 2). If required, the particle shape can be quantified by subsequent computer image analysis.   <\/p>\n<h5>Example \u2013 Surface Chemistry<\/h5>\n<p>Just as particle shape influences the properties during processing or the distribution of particles in the final product, so does surface chemistry (moisture, foreign substances like oils, or targeted surface modifications). Depending on the specific question, different chemical or spectroscopic methods are used here to detect changes in surface chemistry. <\/p>\n<h5>Advantages<\/h5>\n<p>The described methods allow for comprehensive characterization and visualization of particles in powders or suspensions. This enables the analysis of raw materials or products within the scope of quality assurance. The methods are also suitable for determining the cause of problems (e.g., during processing) in case of damage. Furthermore, Analytik Service Obernburg possesses extensive expertise for the analysis of catalysts or fillers in solids.   <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35786\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Partikelgroessenverteilung-zweier-Proben.jpeg\" alt=\"Fig. 1: Particle size distribution of two samples from different production batches.\" width=\"796\" height=\"292\"><\/p>\n<p class=\"p1\"><strong>Fig. 1:<\/strong>  Particle size distribution of two samples from different production batches.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-35787\" src=\"https:\/\/aso-labor.de\/wp-content\/uploads\/2025\/03\/Vergleich-von-Pulvern.jpeg\" alt=\"Fig. 2: Comparison of powders with different agglomeration tendencies.\" width=\"790\" height=\"331\"><\/p>\n<p class=\"p1\"><strong>Fig. 2:<\/strong>  Comparison of powders with different agglomeration tendencies<\/p>\n<\/div><\/div> <script type=\"application\/ld+json\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Material Identification with NMR\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<h4>Material Identification in Medical Technology<\\\/h4>\\n<h5>Problem Statement<\\\/h5>\\n<p>The characterization of medical devices or their underlying raw materials often requires the use of a broad spectrum of analytical and physical methods. This involves a significant time commitment.<br \\\/>However, in many cases, quick material information is needed first, which is then refined later with further analyses. <\\\/p>\\n<h5>Solution<\\\/h5>\\n<p>A versatile method for quickly gaining an overview of a medical device is high-resolution NMR spectroscopy.<br \\\/>It is a method for detailed structural elucidation and quantification of organic substances.<br \\\/>NMR spectroscopy is applicable to all types of organic compounds, including polymers.<br \\\/>Mixtures can be quantified and impurities detected.<\\\/p>\\n<h5>Industries &amp; Applications<\\\/h5>\\n<p><strong>Medical Technology<\\\/strong> \\u2013 Identification of materials and impurities in complex product structures.<\\\/p>\\n<h5>Analysis Objectives<\\\/h5>\\n<p>Rapid material overview for complex matrices for targeted selection of further test procedures.<\\\/p>\\n<h5>Materials<\\\/h5>\\n<p>Composite Materials, Product Formulations<\\\/p>\\n<h5>Analysis Methods<\\\/h5>\\n<ul>\\n<li>\\u00b9H-NMR (Nuclear Magnetic Resonance)<\\\/li>\\n<\\\/ul>\\n<h5>Complementary Methods<\\\/h5>\\n<ul>\\n<li>Extraction<\\\/li>\\n<\\\/ul>\\n<h5>Related Issues<\\\/h5>\\n<ul>\\n<li>Purity Determinations<\\\/li>\\n<li>Release Analytics<\\\/li>\\n<\\\/ul>\\n<h4>Example \\u2013 Heat Patch<\\\/h4>\\n<p>In a commercially available heat patch, the active ingredient <strong>Nonivamide<\\\/strong> is detectable in the spectrum after simple extraction with dichloromethane.<br \\\/>However, further information on the carrier liquid <strong>(1,2-propanediol)<\\\/strong>,<br \\\/>preservative <strong>(4-hydroxybenzoate)<\\\/strong>, adhesive <strong>(acrylate)<\\\/strong>, and fabric material <strong>(polyester)<\\\/strong> can also be read from the spectrum.<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35774\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/beispiel-WAeRMEPFLASTER.jpeg\\\" alt=\\\"\\\" width=\\\"448\\\" height=\\\"301\\\"><\\\/p>\\n<h4>Example \\u2013 Warming Ointment<\\\/h4>\\n<p>In comparison, a spectrum excerpt (only the aromatic region) of the CDCl\\u2083 extract of a warming ointment is shown.<br \\\/>Even without prior processing of the ointment material, the active ingredients <strong>Nicoboxil<\\\/strong> and <strong>Nonivamide<\\\/strong><br \\\/>can be identified and approximately quantified despite the presence of the ointment base.<\\\/p>\\n<p>The quantitative ratio of Nicoboxil to Nonivamide is determined from this spectrum to be approximately <strong>91:9<\\\/strong>,<br \\\/>the package insert for the warming ointment states <strong>86:14<\\\/strong>.<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35775\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/beispiel-waermesalbe.jpeg\\\" alt=\\\"\\\" width=\\\"461\\\" height=\\\"361\\\"><\\\/p>\\n\"}},{\"@type\":\"Question\",\"name\":\"Analytics in Medical Technology\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<h4>Medical Technology<\\\/h4>\\n<p>Medical technology involves the interaction of materials science disciplines with medicine and pharmacy.<br \\\/>Only through this connection is the development and application of complex medical devices possible.<\\\/p>\\n<p>An example of this is artificial blood purification using hemodialysis. Here \\u2013 as shown in Fig. 1 \\u2013 a patient&#8217;s blood is passed through a dialyzer outside their body and then returned.<br \\\/>In the dialyzer, toxins are filtered out of the blood through small pores, while vital components remain in the blood.<br \\\/>Further components of a dialysis machine include the blood pump, tubing systems, and measurement and monitoring devices. Additionally, a medication that acts as an anticoagulant can be administered via the dialysis machine.   <\\\/p>\\n<p>The various components used here must meet high material-technical and medical requirements.<br \\\/>Important material-related topics include, for example, identity testing and characterization of the plastics used, as well as the investigation of material-related damage cases.<\\\/p>\\n<p>Analytik Service Obernburg possesses many years of expertise and a broad spectrum of methods for physical and chemical testing.<br \\\/>With problem-adapted microscopic, spectroscopic, mechanical, or thermoanalytical investigations \\u2013 possibly also in suitable combination \\u2013 a clarification of the respective issue can be achieved quickly and cost-effectively.<br \\\/>Three typical examples are presented below.<\\\/p>\\n<h5>Industries &amp; Applications<\\\/h5>\\n<p><strong>Medical Technology<\\\/strong> \\u2013 Analysis of devices, components, and materials from medical practice.<\\\/p>\\n<h5>Analysis Objectives<\\\/h5>\\n<p>Failure Analysis and Material Identification of Components and Plastics.<\\\/p>\\n<h5>Materials<\\\/h5>\\n<p>Membranes, Tubes, Injection Needles<\\\/p>\\n<h5>Analysis Methods<\\\/h5>\\n<ul>\\n<li>Scanning Electron Microscopy (SEM-EDX)<\\\/li>\\n<li>IR Spectroscopy<\\\/li>\\n<li>ESCA \\\/ XPS<\\\/li>\\n<\\\/ul>\\n<h4>Example \\u2013 Defective Capillary Membrane in a Dialyzer of a Dialysis Machine<\\\/h4>\\n<p>The filtration behavior of purchased capillary membranes was found to be faulty.<br \\\/>Due to the small structures of the defective hollow fiber membrane, it was examined in cross-section using scanning electron microscopy (SEM) (Fig. 2).<br \\\/>Large voids are visible in the membrane wall. The SEM detailed image indicates that the void is connected to the inner channel (lumen) of the capillary membrane (arrow in Fig. 2). <br \\\/>The large voids reduce the effectively active wall surface of the capillary membrane to up to one third of the normal value, thus representing the reason for the observed reduction in function.<\\\/p>\\n<h4>Example \\u2013 Identification Testing of Plastic Materials<\\\/h4>\\n<p>The identification of plastics used in device components such as plastic housings, membranes, or tubing systems is carried out using infrared spectroscopy (FTIR).<br \\\/>The signals in the FTIR spectrum (Fig. 3) can be precisely assigned to the materials used, which is crucial for failure analysis or complaint processing.<br \\\/>The microscopic variant of FTIR analysis is also used for identifying the smallest (from 15 \\u00b5m in size) organic particles or deposits, e.g., in tubing systems.<\\\/p>\\n<h4>Example \\u2013 Material Surfaces in Contact with Biological Media<\\\/h4>\\n<p>For material surfaces (cannulas, membranes, tubes, etc.) that come into contact with body tissue or blood, the surface-sensitive analytical method ESCA\\\/XPS (information depth of a few nm) is preferably used,<br \\\/>to investigate contaminations, coatings, or biocompatibility. An application example is shown in Fig. 4.<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35776\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Abb.-1-Prinzip-der-kuenstliche-Blutwaesche-Haemodialyse.jpeg\\\" alt=\\\"\\\" width=\\\"463\\\" height=\\\"273\\\"><\\\/p>\\n<p>Fig. 1 \\u2013 Principle of Artificial Blood Purification (Hemodialysis) <\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35777\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Abb.-2-REM-Querschnittsaufnahme-des-Schadensbereichs.jpeg\\\" alt=\\\"\\\" width=\\\"603\\\" height=\\\"452\\\"><\\\/p>\\n<p>Fig. 2 \\u2013 SEM Cross-sectional View of the Damaged Area <\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35778\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/FTIP-Spektrum.jpeg\\\" alt=\\\"Fig. 3: FTIR spectrum of polycarbonate (PC), a material frequently used for transparent housing parts\\\" width=\\\"784\\\" height=\\\"449\\\"><\\\/p>\\n<p class=\\\"p1\\\">Fig. 3: FTIR spectrum of polycarbonate (PC), a material frequently used for transparent housing parts <\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35779\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Spitze-einer-Hohlkanuele.jpeg\\\" alt=\\\"Fig. 4: Tip of a hollow cannula and the element concentrations found with ESCA in the uppermost nanometers of the cannula's outer surface, indicating a silicone layer\\\" width=\\\"723\\\" height=\\\"386\\\"><\\\/p>\\n<p class=\\\"p1\\\">Fig. 4: Tip of a hollow cannula and the element concentrations found with ESCA in the uppermost nanometers of the cannula&#8217;s outer surface, indicating a silicone layer <\\\/p>\\n\"}},{\"@type\":\"Question\",\"name\":\"Molecular Weight Distribution\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<h4>Polymer Characterization Using GPC \\u2013 Quality Testing for Plastics<\\\/h4>\\n<h5>Problem Statement<\\\/h5>\\n<p>Even if polymers are composed of the same monomers, their properties can differ. The polymer chains of a material exhibit varying chain lengths or masses. The resulting mass distribution has a decisive influence on the properties of the final plastic.<br \\\/>Conscious or unconscious deviations in the manufacturing procedure can thus lead to undesirable changes and result in processing difficulties or quality defects.<br \\\/>Unsuitable parameters of molding processes can also lead to thermal degradation and thus to a decrease in chain lengths in the product.  <\\\/p>\\n<h5>Solution<\\\/h5>\\n<p>Analytik Service Obernburg offers polymer analyses using GPC (Gel Permeation Chromatography).<br \\\/>In this technique, a sample of the test material is dissolved in a solvent, applied to a separation column, and pumped towards the detector.<br \\\/>The sample molecules are retained to varying degrees depending on their size (more precisely: their hydrodynamic volume) by a special separation material, thus reaching the detector at different times.<\\\/p>\\n<h5>Industries &amp; Applications<\\\/h5>\\n<ul>\\n<li>Chemical Companies<\\\/li>\\n<li>Plastics Processors<\\\/li>\\n<li>Medical Technology<\\\/li>\\n<\\\/ul>\\n<h5>Analysis Objectives<\\\/h5>\\n<ul>\\n<li>Assessment of Product Quality<\\\/li>\\n<\\\/ul>\\n<h5>Materials<\\\/h5>\\n<ul>\\n<li>Polymers<\\\/li>\\n<li>Polymers<\\\/li>\\n<\\\/ul>\\n<h5>Analysis Methods<\\\/h5>\\n<ul>\\n<li>Gel Permeation Chromatography (GPC)<\\\/li>\\n<\\\/ul>\\n<h5>Related Issues<\\\/h5>\\n<ul>\\n<li>Release Tests<\\\/li>\\n<li>Oligomer Content<\\\/li>\\n<\\\/ul>\\n<h5>Solution<\\\/h5>\\n<p>With the help of suitable reference materials of known molecular size, the average molar mass for the sample is finally obtained. This can be calculated in different ways (Mn, Mw, Mz) and thus provides several statistical parameters for production control.<br \\\/>Furthermore, the polydispersity D, which describes the width of the molar mass distribution, is determined. By comparing these parameters for two batches of a product, deviations and process errors can be quickly identified if necessary.  <\\\/p>\\n<h5>Advantages<\\\/h5>\\n<p>At Analytik Service Obernburg, the most common THF-soluble polymers can be analyzed (including PMMA, PS, PC, SAN).<br \\\/>This simple procedure provides timely and meaningful values for quality control or product development.<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35780\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/ACRYLAT-KOMPONENTE.jpeg\\\" alt=\\\"Fig. 1:&lt;\\\/strong&gt; Acrylate component of an embedding medium. Among other things, the final hardness is influenced by the average molar mass of the polymer.\\\" width=\\\"415\\\" height=\\\"313\\\"><\\\/p>\\n<p class=\\\"p1\\\"><strong>Fig. 1:<\\\/strong> Acrylate component of an embedding medium. Among other things, the final hardness is influenced by the average molar mass of the polymer.<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35781\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/SCHEMATISCHE-DARSTELLUNG-DER-MOLEKUeLTRENNUNG.jpeg\\\" alt=\\\"Fig. 2: Schematic representation of molecular separation (left) and example of a detector signal for a SAN sample (right)\\\" width=\\\"965\\\" height=\\\"433\\\"><\\\/p>\\n<p><strong>Fig. 2:<\\\/strong> Schematic representation of molecular separation (left) and example of a detector signal for a SAN sample (right)<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35782\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/1b35f835-11e2-476e-ba14-b5670186b5f7.jpeg\\\" alt=\\\"Fig. 3: GPC system; left: oven containing the separation column(s); center: autosampler and detector; right: pump and solvent reservoir with degassing unit.\\\" width=\\\"718\\\" height=\\\"390\\\"><\\\/p>\\n<p class=\\\"p1\\\"><strong>Fig. 3:<\\\/strong> GPC system; left: oven containing the separation column(s); center: autosampler and detector; right: pump and solvent reservoir with degassing unit.<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35783\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Diagramm-der-molmassenvereilung.jpeg\\\" alt=\\\"Fig. 4: Diagram of the molar mass distribution of a SAN sample, as well as the most important determined molar masses and the polydispersity D.\\\" width=\\\"918\\\" height=\\\"409\\\"><\\\/p>\\n<p class=\\\"p1\\\"><strong>Fig. 4:<\\\/strong> Diagram of the molar mass distribution of a SAN sample, as well as the most important determined molar masses and the polydispersity D.<\\\/p>\\n\"}},{\"@type\":\"Question\",\"name\":\"Phase Purity with X-ray Diffraction\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<h4>X-ray Diffraction \\u2013 Purity Analysis of Bone Substitutes<\\\/h4>\\n<h5>Problem Statement<\\\/h5>\\n<p>The mineral hydroxylapatite \\u2013 Ca5(OH)(PO4)3 \\u2013 is a main component of human bone substance and has proven itself as an implant material for surgical applications.<br \\\/>Calcium compounds exist with a similar chemical composition but with a different crystal structure and consequently altered or undesirable properties regarding biocompatibility or resorption rate.<\\\/p>\\n<h5>Solution<\\\/h5>\\n<p>X-ray diffraction allows the identification and quantitative detection of foreign phases.<br \\\/>For the example shown in Figure 1, the hydroxylapatite contains traces of calcium oxide (marked by reflections with arrows).<br \\\/>The method is described in standard ISO 13779-3.<br \\\/>Another important property that can be determined by X-ray diffraction is the degree of crystallinity of the sample.<br \\\/>Amorphous components demonstrably have higher solubility and can be resorbed more quickly in the body.<br \\\/>An evaluation of the peak width in the diffraction pattern allows conclusions about crystallite size.<br \\\/>The size and shape of hydroxylapatite crystals (HA) are additionally investigated using electron microscopy (see Fig. 2).<\\\/p>\\n<h5>Industries &amp; Applications<\\\/h5>\\n<ul>\\n<li>Medical Technology<\\\/li>\\n<\\\/ul>\\n<h5>Objectives<\\\/h5>\\n<p>Product Development, Quality Assurance, Failure Analysis<\\\/p>\\n<h5>Materials<\\\/h5>\\n<p>Crystalline Solids, Bone Cements<\\\/p>\\n<h5>Analysis Methods<\\\/h5>\\n<ul>\\n<li>X-ray Diffractometry (XRD)<\\\/li>\\n<li>Wide-Angle X-ray Scattering (WAXS)<\\\/li>\\n<\\\/ul>\\n<h5>Complementary Methods<\\\/h5>\\n<ul>\\n<li>X-ray Fluorescence (XRF)<\\\/li>\\n<li>Electron Microscopy<\\\/li>\\n<\\\/ul>\\n<h5>Advantages<\\\/h5>\\n<p>X-ray diffraction allows statements regarding phase purity, crystallinity, and crystallite size. These are parameters that must be checked for quality assurance according to standards. In addition to the application example from medical technology, this technique can also distinguish various modifications of the white pigment titanium dioxide or various calcium sulfates (gypsum, bassanite, anhydrite, etc.). For the analysis of hydroxylapatite, Analytik Service Obernburg GmbH also offers the possibility to analyze the Ca:P ratio and heavy metal freedom by X-ray fluorescence (XRF). The ICP-OES method allows the analysis of heavy metal impurities even in the lowest concentrations.    <\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35785\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Beugungsdiagramm-einer-Pulverprobe.jpeg\\\" alt=\\\"Figure 1: Diffraction pattern of a powder sample plotted as intensity versus diffraction angle (blue line, top). For comparison, below are reflection positions and intensities from a database for hydroxylapatite (green) and calcium oxide (red).\\\" width=\\\"758\\\" height=\\\"544\\\"><\\\/p>\\n<p><strong>Figure 1:<\\\/strong> Diffraction pattern of a powder sample plotted as intensity versus diffraction angle (blue line, top). For comparison, below are reflection positions and intensities from a database for hydroxylapatite (green) and calcium oxide (red). <\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35784\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Visualisierung-der-Nadelstruktur.jpeg\\\" alt=\\\"Figure 2: Visualization of the needle structure and size of hydroxylapatite crystals using transmission electron microscopy.\\\" width=\\\"885\\\" height=\\\"620\\\"><\\\/p>\\n<p><strong>Figure 2:<\\\/strong> Visualization of the needle structure and size of hydroxylapatite crystals using transmission electron microscopy.<\\\/p>\\n\"}},{\"@type\":\"Question\",\"name\":\"Particle Size Analysis PMMA\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<h4>Particle Analysis \\u2013 Characterization of Powders and Suspensions<\\\/h4>\\n<h5>Problem Statement<\\\/h5>\\n<p>The processing properties of a powder or suspension critically depend on the particle size, particle shape, and surface chemistry of the particles. Thus, one powder may flow finely, while another tends to clump. Particles that are too large can clog filters, while particles that are too small can cause significant dust formation during further processing. This is just a small selection of issues attributable to different particle properties.   <\\\/p>\\n<h5>Solution<\\\/h5>\\n<p>At Analytik Service Obernburg, various analytical methods are used for particle characterization, which will be discussed in more detail below.<\\\/p>\\n<h5>Industries &amp; Applications<\\\/h5>\\n<ul>\\n<li>Medical Technology<\\\/li>\\n<li>Paint Manufacturers<\\\/li>\\n<li>Compounders<\\\/li>\\n<\\\/ul>\\n<h5>Analysis Objectives<\\\/h5>\\n<ul>\\n<li>Determination of Particle Size<\\\/li>\\n<li>Assessment of Particle Shape<\\\/li>\\n<li>Investigation of Agglomeration Tendency<\\\/li>\\n<\\\/ul>\\n<h5>Materials<\\\/h5>\\n<ul>\\n<li>Powders<\\\/li>\\n<li>Suspensions<\\\/li>\\n<\\\/ul>\\n<h5>Analysis Methods<\\\/h5>\\n<ul>\\n<li>Laser Diffraction<\\\/li>\\n<li>Scanning Electron Microscopy (SEM-EDX)<\\\/li>\\n<\\\/ul>\\n<h5>Example \\u2013 Particle Size Distribution<\\\/h5>\\n<p>The determination of particle size distribution is carried out using laser diffraction. Particles between 0.1 \\u00b5m and 2000 \\u00b5m can be measured. A distribution curve is obtained, from which the particle size can be read, as well as various statistical values describing the distribution (Fig. 1). These values can be directly used for validating the manufacturing process in quality assurance. The test is performed on the powder dispersed in water. By measuring with and without ultrasound, a distinction can be made between agglomerates and primary particles.     <\\\/p>\\n<h5>Example \\u2013 Particle Shape<\\\/h5>\\n<p>Various microscopic measurement methods are available for investigating particle shape \\u2013 from light microscopy to electron microscopy (SEM) and atomic force microscopy (AFM). These methods allow not only the characterization of the particle&#8217;s shape but also its surface fine structure. Both are crucial for the interaction between particles (e.g., agglomeration tendency) (Fig. 2). If required, the particle shape can be quantified by subsequent computer image analysis.   <\\\/p>\\n<h5>Example \\u2013 Surface Chemistry<\\\/h5>\\n<p>Just as particle shape influences the properties during processing or the distribution of particles in the final product, so does surface chemistry (moisture, foreign substances like oils, or targeted surface modifications). Depending on the specific question, different chemical or spectroscopic methods are used here to detect changes in surface chemistry. <\\\/p>\\n<h5>Advantages<\\\/h5>\\n<p>The described methods allow for comprehensive characterization and visualization of particles in powders or suspensions. This enables the analysis of raw materials or products within the scope of quality assurance. The methods are also suitable for determining the cause of problems (e.g., during processing) in case of damage. Furthermore, Analytik Service Obernburg possesses extensive expertise for the analysis of catalysts or fillers in solids.   <\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35786\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Partikelgroessenverteilung-zweier-Proben.jpeg\\\" alt=\\\"Fig. 1: Particle size distribution of two samples from different production batches.\\\" width=\\\"796\\\" height=\\\"292\\\"><\\\/p>\\n<p class=\\\"p1\\\"><strong>Fig. 1:<\\\/strong>  Particle size distribution of two samples from different production batches.<\\\/p>\\n<p><img class=\\\"alignnone size-full wp-image-35787\\\" src=\\\"https:\\\/\\\/aso-labor.de\\\/wp-content\\\/uploads\\\/2025\\\/03\\\/Vergleich-von-Pulvern.jpeg\\\" alt=\\\"Fig. 2: Comparison of powders with different agglomeration tendencies.\\\" width=\\\"790\\\" height=\\\"331\\\"><\\\/p>\\n<p class=\\\"p1\\\"><strong>Fig. 2:<\\\/strong>  Comparison of powders with different agglomeration tendencies<\\\/p>\\n\"}}]}<\/script> <\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Our range of services includes the control of active ingredient content and the testing for impurities.<\/p>\n","protected":false},"featured_media":37356,"parent":0,"menu_order":0,"template":"","format":"standard","meta":{"_seowing_meta_title":"Medical Devices | Analytics in Regulated Environment | ASO","_seowing_meta_description":"Testing for medical devices: approval testing, biocompatibility, bone cement, bone substitutes and membrane analysis.","_seowing_focus_keyword":"Medical Devices Testing Analytics","_seowing_canonical_url":"","_seowing_robots":"","_seowing_robots_noindex":false,"_seowing_robots_nofollow":false,"_seowing_seo_score":68,"_expert_id":0},"tags":[],"class_list":["post-37335","branchen","type-branchen","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/branchen\/37335","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/branchen"}],"about":[{"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/types\/branchen"}],"version-history":[{"count":3,"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/branchen\/37335\/revisions"}],"predecessor-version":[{"id":45772,"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/branchen\/37335\/revisions\/45772"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/media\/37356"}],"wp:attachment":[{"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/media?parent=37335"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aso-labor.de\/en\/wp-json\/wp\/v2\/tags?post=37335"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}